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| Cat.No | ACP12316 | Target Name | TRIM54 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-358 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BYV2 |
|---|
Uniprot Id
Q9BYV2
Target Species
Human
Target Name
TRIM54
Target Full Name
Tripartite motif-containing protein 54
Target Function
May bind and stabilize microtubules during myotubes formation.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
Target Tissue Specificity
Specifically expressed in heart and skeletal muscle.
Target Synonyms
MURF 3; MuRF; MURF-3; MuRF3; Muscle specific RING finger protein 3; Muscle specific RING finger protein; Muscle specific RING finger protein homolog; Muscle-specific RING finger protein 3; Muscle-specific RING finger protein; RING finger protein 30; RNF30; TRI54_HUMAN; TRIM 54; Trim54; Tripartite motif containing 54 ; Tripartite motif containing protein 54; Tripartite motif-containing protein 54
Target Background
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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