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Recombinant Human Tubby-related protein 3 (TULP3)

ACP21077

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Specifications

Cat.No	ACP21077	Target Name	TULP3
Target Synonyms	MGC45295; Tubby like protein 3; Tubby related protein 3; Tubby-like protein 3; Tubby-related protein 3; TUBL 3; TUBL3; TULP 3; TULP3; TULP3_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-442
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O75386

Background Information

Uniprot Id

O75386
Target Species

Human
Target Name

TULP3
Target Full Name

Tubby-related protein 3
Target Function

Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
Target Subcellular Location

Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted.
Target Protein Families

TUB family
Target Tissue Specificity

Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
Target Synonyms

MGC45295; Tubby like protein 3; Tubby related protein 3; Tubby-like protein 3; Tubby-related protein 3; TUBL 3; TUBL3; TULP 3; TULP3; TULP3_HUMAN

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Recombinant Human Tubby-related protein 3 (TULP3)

Specifications

Immunogen Information

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