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| Cat.No | ACP13831 | Target Name | PTH2 |
|---|---|---|---|
| Target Synonyms | PTH2; TIP39; TIPF39; Tuberoinfundibular peptide of 39 residues; TIP39; Parathyroid hormone 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 62-100 |
| Protein Length | Cytoplasmic Domain | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96A98 |
|---|
Uniprot Id
Q96A98
Target Species
Human
Target Name
PTH2
Target Full Name
Tuberoinfundibular peptide of 39 residues
Target Function
Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits.
Target Subcellular Location
Secreted.
Target Protein Families
Parathyroid hormone family
Target Tissue Specificity
Highly expressed in fetal and adult brain, cerebellum and trachea. Weakly expressed in spinal cord, fetal liver, kidney and heart.
Target Synonyms
PTH2; TIP39; TIPF39; Tuberoinfundibular peptide of 39 residues; TIP39; Parathyroid hormone 2
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