Home Products Uncategorized Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), Truncated

Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), Truncated

ACP00914

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Specifications

Cat.No	ACP00914	Target Name	Tnfrsf4
Form	Liquid or Lyophilized powder	Expression System	Mammalian cell
Expression Range	29-216aa	Mol Weight	49.3 kDa
Protein Length	Partial	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P43489

Background Information

Uniprot Id

P43489
Target Species

Human
Target Name

TNFRSF4
Target Full Name

Tumor necrosis factor receptor superfamily member 4
Target Function

Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.; (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.
Target Involvement

Immunodeficiency 16 (IMD16)
Target Subcellular Location

Membrane; Single-pass type I membrane protein.
Target Research Area

Immunology
Target Synonyms

TNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD antigen CD134
Target Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

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Recombinant Human Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), Truncated

Specifications

Immunogen Information

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