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| Cat.No | ACP02237 | Target Name | SNRNP70 |
|---|---|---|---|
| Target Synonyms | SNRNP70; RNPU1Z; RPU1; SNRP70; U1AP1U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-210aa |
| Mol Weight | 28.7 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P08621 |
|---|
Uniprot Id
P08621
Target Species
Human
Target Name
SNRNP70
Target Full Name
U1 small nuclear ribonucleoprotein 70 kDa
Target Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.
Target Subcellular Location
Nucleus speckle. Nucleus, nucleoplasm.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
SNRNP70; RNPU1Z; RPU1; SNRP70; U1AP1U1 small nuclear ribonucleoprotein 70 kDa; U1 snRNP 70 kDa; U1-70K; snRNP70
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