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The preparation of the recombinant Human USP26 protein involves manipulating the expression of the desired gene in e.coli cells. The sequence (291-890aa) of foreign DNA is fused to an expression vector and then introduced into e.coli cells. Selected positive cells are cultured to induce the expression of the desired protein. The protein features a N-terminal 6xHis tag fusion. The recombinant targeted protein is subjected to affinity purification. Its purity exceeds 85% as assessed by SDS-PAGE.
The preparation of the recombinant Human USP26 protein involves manipulating the expression of the desired gene in e.coli cells. The sequence (291-890aa) of foreign DNA is fused to an expression vector and then introduced into e.coli cells. Selected positive cells are cultured to induce the expression of the desired protein. The protein features a N-terminal 6xHis tag fusion. The recombinant targeted protein is subjected to affinity purification. Its purity exceeds 85% as assessed by SDS-PAGE.
| Cat.No | ACP01158 | Target Name | USP26 |
|---|---|---|---|
| Target Synonyms | (Deubiquitinating enzyme 26)(Ubiquitin thioesterase 26)(Ubiquitin-specific-processing protease 26) | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 291-890aa |
| Mol Weight | 72.4 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BXU7 |
|---|
Uniprot Id
Q9BXU7
Target Species
Human
Target Name
USP26
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 26
Target Function
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.
Target Subcellular Location
Nucleus.
Target Protein Families
Peptidase C19 family
Target Research Area
Others
Target Synonyms
Deubiquitinating enzyme 26; MGC120066; MGC120067; MGC120068; Ubiquitin carboxyl terminal hydrolase 26; Ubiquitin carboxyl-terminal hydrolase 26; Ubiquitin specific peptidase 26; Ubiquitin specific processing protease 26; Ubiquitin specific protease 26; Ubiquitin thioesterase 26; Ubiquitin thiolesterase 26; Ubiquitin-specific-processing protease 26; UBP26_HUMAN; USP 26; USP26
Target Background
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases and is a deubiquitinating enzyme (DUB) with His and Cys domains. It is specifically expressed in testis tissue. Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility.
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