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| Cat.No | ACP16402 | Target Name | USP34 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q70CQ2 |
|---|
Uniprot Id
Q70CQ2
Target Species
Human
Target Name
USP34
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 34
Target Function
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Target Protein Families
Peptidase C19 family
Target Tissue Specificity
Expressed in brain at low level.
Target Synonyms
Deubiquitinating enzyme 34; FLJ43910; KIAA0570; KIAA0729; MGC104459; Ubiquitin carboxyl terminal hydrolase 34; Ubiquitin carboxyl-terminal hydrolase 34; Ubiquitin specific processing protease 34; Ubiquitin specific protease 34; Ubiquitin thioesterase 34; Ubiquitin thiolesterase 34; Ubiquitin-specific-processing protease 34; UBP34_HUMAN; USP 34; Usp34
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