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| Cat.No | ACP05590 | Target Name | SLC35A2 |
|---|---|---|---|
| Target Synonyms | SLC35A2; UGALT; UGT; UGTL; UDP-galactose translocator; Solute carrier family 35 member A2; UDP-galactose transporter; UDP-Gal-Tr; UGT | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P78381 |
|---|
Uniprot Id
P78381
Target Species
Human
Target Name
SLC35A2
Target Full Name
UDP-galactose translocator
Target Function
Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
Target Involvement
Congenital disorder of glycosylation 2M (CDG2M)
Target Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Target Protein Families
Nucleotide-sugar transporter family, SLC35A subfamily
Target Synonyms
SLC35A2; UGALT; UGT; UGTL; UDP-galactose translocator; Solute carrier family 35 member A2; UDP-galactose transporter; UDP-Gal-Tr; UGT
Target Background
This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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