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| Cat.No | ACP14558 | Target Name | B3GALNT2 |
|---|---|---|---|
| Target Synonyms | 3 galactosaminyltransferase 2; Beta 1, 3 galactosaminyltransferase polypeptide 2; UDP-GalNAc:beta-1; UDP-GalNAc:beta-1, 3 N acetylgalactosaminyltransferase 2; Beta 1, 3 N acetylgalactosaminyltransferase II MGC39558; Beta 3 GalNAc T2; Beta-1; beta-1, 3 N acetylgalactosaminyltransferase II; Beta 1, 3-GalNAc-T2; 3-N-acetylgalactosaminyltransferase 2; 3-N-acetylgalactosaminyltransferase II; B3GalNAc T2; B3GalNAcT2; b3galnt2; B3GL2_HUMAN; Beta 1, 3-GalNAc-T2; Beta3GalNAcT2; MDDGA11; MGC39558; UDP GalNAc:betaGlcNAc beta 1, 3-N-acetylgalactosaminyltransferase 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NCR0 |
|---|
Uniprot Id
Q8NCR0
Target Species
Human
Target Name
B3GALNT2
Target Full Name
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
Target Function
Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
Target Involvement
Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A11 (MDDGA11)
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum.
Target Protein Families
Glycosyltransferase 31 family
Target Tissue Specificity
Expressed in all tissues examined, but at highest levels in testis, adipose tissue, skeletal muscle and ovary.
Target Synonyms
3-GalNAc-T2; 3-N-acetylgalactosaminyltransferase 2; 3-N-acetylgalactosaminyltransferase II; B3GalNAc T2; B3GalNAcT2; b3galnt2; B3GL2_HUMAN; Beta 1,3 galactosaminyltransferase 2; Beta 1,3 N acetylgalactosaminyltransferase 2; Beta 1,3 N acetylgalactosaminyltransferase II; Beta 1,3 N acetylgalactosaminyltransferase II MGC39558; Beta 3 GalNAc T2; Beta-1; beta-1,3-GalNAc-T2; Beta3GalNAcT2; MDDGA11; MGC39558; UDP GalNAc:betaGlcNAc beta 1,3 galactosaminyltransferase polypeptide 2; UDP-GalNAc:beta-1; UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
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