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| Cat.No | ACP07320 | Target Name | UGT2B28 |
|---|---|---|---|
| Target Synonyms | UGT2B28; UDP-glucuronosyltransferase 2B28; UDPGT 2B28; UGT2B28 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BY64 |
|---|
Uniprot Id
Q9BY64
Target Species
Human
Target Name
UGT2B28
Target Full Name
UDP-glucuronosyltransferase 2B28
Target Function
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (androsterone, 3alpha-androstanediol) and estrogens (estradiol, estrone). Catalyzes the glucuronidation of bile acid substrates, which are natural detergents for dietary lipids absorption. Displays glucuronidation activity toward the phenolic compounds eugenol.; Lack UDP-glucuronosyltransferase (UGT) activity
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm, perinuclear region.
Target Protein Families
UDP-glycosyltransferase family
Target Tissue Specificity
Expressed in the liver, breast and kidney.
Target Synonyms
UGT2B28; UDP-glucuronosyltransferase 2B28; UDPGT 2B28; UGT2B28
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