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| Cat.No | ACP10602 | Target Name | ALG13 |
|---|---|---|---|
| Target Synonyms | ALG13; ALG13, homolog of; ALG13, S. cerevisiae, UDP-N-acetylglucosaminyltransferase subunit; ALG13_HUMAN; Asparagine linked glycosylation 13 homolog (S. cerevisiae); Asparagine-linked glycosylation 13 homolog; Asparagine-linked glycosylation 13 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NP73 |
|---|
Uniprot Id
Q9NP73
Target Species
Human
Target Name
ALG13
Target Full Name
UDP-N-acetylglucosamine transferase subunit ALG13
Target Function
Possible multifunctional enzyme with both glycosyltransferase and deubiquitinase activities.; May be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway.
Target Involvement
Epileptic encephalopathy, early infantile, 36 (EIEE36)
Target Subcellular Location
[Isoform 2]: Endoplasmic reticulum. Note=Could be recruited to the cytosolic face of the endoplasmic reticulum membrane through its interaction with ALG14.
Target Protein Families
Glycosyltransferase 28 family
Target Synonyms
ALG13; ALG13, S. cerevisiae, homolog of; ALG13, UDP-N-acetylglucosaminyltransferase subunit; ALG13_HUMAN; Asparagine linked glycosylation 13 homolog (S. cerevisiae); Asparagine-linked glycosylation 13 homolog; Asparagine-linked glycosylation 13, S. cerevisiae, homolog of; CDG1S; CXorf45; FLJ23018; FLJ31785; GLT28D1; Glycosyltransferase 28 domain containing protein 1 ; Glycosyltransferase 28 domain-containing 1; Glycosyltransferase 28 domain-containing protein 1; Hematopoietic stem/progenitor cells protein MDS031; MDS031; MGC12423; N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase; OTTHUMP00000062812; OTTHUMP00000176862; TDRD13; tudor domain containing 13; UDP N acetylglucosamine transferase subunit ALG13 homolog; UDP-N-acetylglucosamine transferase subunit ALG13 homolog; YGL047W
Target Background
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene.
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