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| Cat.No | ACP17289 | Target Name | NCBP3 |
|---|---|---|---|
| Target Synonyms | C17orf85; Chromosome 17 open reading frame 85; CQ085_HUMAN; ELG; HSA277841; Protein ELG; Uncharacterized protein C17orf85 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-620 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q53F19 |
|---|
Uniprot Id
Q53F19
Target Species
Human
Target Name
NCBP3
Target Full Name
Nuclear cap-binding protein subunit 3
Target Function
Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
NCBP3 family
Target Synonyms
C17orf85; Chromosome 17 open reading frame 85; CQ085_HUMAN; ELG; HSA277841; Protein ELG; Uncharacterized protein C17orf85
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