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| Cat.No | ACP21992 | Target Name | EPOP |
|---|---|---|---|
| Target Synonyms | C17orf96; Chromosome 17 open reading frame 96; CQ096_HUMAN; Uncharacterized protein C17orf96 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-379 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A6NHQ4 |
|---|
Uniprot Id
A6NHQ4
Target Species
Human
Target Name
EPOP
Target Full Name
Elongin BC and Polycomb repressive complex 2-associated protein
Target Function
Scaffold protein that serves as a bridging partner between the PRC2/EZH2 complex and the elongin BC complex: required to fine-tune the transcriptional status of Polycomb group (PcG) target genes in embryonic stem cells (ESCs). Plays a key role in genomic regions that display both active and repressive chromatin properties in pluripotent stem cells by sustaining low level expression at PcG target genes: acts by recruiting the elongin BC complex, thereby restricting excessive activity of the PRC2/EZH2 complex. Interaction with USP7 promotes deubiquitination of H2B at promoter sites. Acts as a regulator of neuronal differentiation
Target Subcellular Location
Nucleus. Chromosome.
Target Synonyms
C17orf96; Chromosome 17 open reading frame 96; CQ096_HUMAN; Uncharacterized protein C17orf96
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