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Recombinant Human Unconventional myosin-XV (MYO15A), Truncated

ACP10058

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10058 Target NameMYO15A
Target SynonymsDFNB3; MYO15; MYO15_HUMAN; MYO15A; Myosin XV; Myosin XVA; Unconventional myosin 15; Unconventional myosin XV; Unconventional myosin-15; Unconventional myosin-XVFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UKN7
Background Information
  • Uniprot Id

    Q9UKN7

  • Target Species

    Human

  • Target Name

    MYO15A

  • Target Full Name

    Unconventional myosin-XV

  • Target Function

    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles.

  • Target Involvement

    Deafness, autosomal recessive, 3 (DFNB3)

  • Target Subcellular Location

    Cell projection, stereocilium. Cytoplasm, cytoskeleton.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Myosin family

  • Target Tissue Specificity

    Highly expressed in pituitary. Also expressed at lower levels in adult brain, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in brain. In the pituitary, highly expressed in anterior gland cells.

  • Target Synonyms

    DFNB3; MYO15; MYO15_HUMAN; MYO15A; Myosin XV; Myosin XVA; Unconventional myosin 15; Unconventional myosin XV; Unconventional myosin-15; Unconventional myosin-XV

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