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| Cat.No | ACP15773 | Target Name | KIAA1324 |
|---|---|---|---|
| Target Synonyms | EIG121; Estrogen induced gene 121; Estrogen-induced gene 121 protein; Hypothetical protein LOC57535; K1324_HUMAN; KIAA1324; MABA1; MGC150624; UPF0577 protein KIAA1324 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UXG2 |
|---|
Uniprot Id
Q6UXG2
Target Species
Human
Target Name
ELAPOR1
Target Full Name
Endosome/lysosome-associated apoptosis and autophagy regulator 1
Target Function
May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. May play a role in apoptosis and cell proliferation through its interaction with HSPA5.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Target Protein Families
UPF0577 family
Target Tissue Specificity
Expressed in normal endometrium but overexpressed in endometroid tumors.
Target Synonyms
EIG121; Estrogen induced gene 121; Estrogen-induced gene 121 protein; Hypothetical protein LOC57535; K1324_HUMAN; KIAA1324; MABA1; MGC150624; UPF0577 protein KIAA1324
Target Background
Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants.
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