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| Cat.No | ACP18968 | Target Name | VAX2 |
|---|---|---|---|
| Target Synonyms | VAX2; Ventral anterior homeobox 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-290 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UIW0 |
|---|
Uniprot Id
Q9UIW0
Target Species
Human
Target Name
VAX2
Target Full Name
Ventral anterior homeobox 2
Target Function
Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle. May be a regulator of axial polarization in the retina.
Target Subcellular Location
Nucleus.
Target Protein Families
EMX homeobox family
Target Synonyms
VAX2; Ventral anterior homeobox 2
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