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| Cat.No | ACP05962 | Target Name | SLC17A8 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NDX2 |
|---|
Uniprot Id
Q8NDX2
Target Species
Human
Target Name
SLC17A8
Target Full Name
Vesicular glutamate transporter 3
Target Function
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
Target Involvement
Deafness, autosomal dominant, 25 (DFNA25)
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
Target Protein Families
Major facilitator superfamily, Sodium/anion cotransporter family, VGLUT subfamily
Target Tissue Specificity
Expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus.
Target Synonyms
deafness autosomal dominant 25; DFNA 25; DFNA25; SLC17A8; Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8; Solute carrier family 17 member 8; Vesicular glutamate transporter 3; VGLU3_HUMAN; VGLUT 3; VGluT3
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