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Recombinant Human Voltage-dependent calcium channel gamma-8 subunit (CACNG8), Truncated

ACP07934

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP07934 Target NameCACNG8
Target SynonymsCACNG8; CACNG6; Voltage-dependent calcium channel gamma-8 subunit; Neuronal voltage-gated calcium channel gamma-8 subunit; Transmembrane AMPAR regulatory protein gamma-8; TARP gamma-8FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8WXS5
Background Information
  • Uniprot Id

    Q8WXS5

  • Target Species

    Human

  • Target Name

    CACNG8

  • Target Full Name

    Voltage-dependent calcium channel gamma-8 subunit

  • Target Function

    Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density membrane.

  • Target Protein Families

    PMP-22/EMP/MP20 family, CACNG subfamily

  • Target Tissue Specificity

    Detected in heart left ventricle.

  • Target Synonyms

    CACNG8; CACNG6; Voltage-dependent calcium channel gamma-8 subunit; Neuronal voltage-gated calcium channel gamma-8 subunit; Transmembrane AMPAR regulatory protein gamma-8; TARP gamma-8

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