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| Cat.No | ACP06075 | Target Name | WDFY4 |
|---|---|---|---|
| Target Synonyms | WDFY4; C10orf64; KIAA1607WD repeat- and FYVE domain-containing protein 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZS81 |
|---|
Uniprot Id
Q6ZS81
Target Species
Human
Target Name
WDFY4
Target Full Name
WD repeat- and FYVE domain-containing protein 4
Target Function
Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
Target Subcellular Location
Early endosome. Endoplasmic reticulum.
Target Synonyms
WDFY4; C10orf64; KIAA1607WD repeat- and FYVE domain-containing protein 4
Target Background
Predicted to be involved in autophagy. Predicted to act upstream of or within with a positive effect on CD8-positive, alpha-beta T cell activation. Predicted to act upstream of or within antigen processing and presentation and cellular response to virus. Predicted to be located in early endosome and endoplasmic reticulum.
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