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| Cat.No | ACP12945 | Target Name | ZUFSP |
|---|---|---|---|
| Target Synonyms | ZUP1; C6orf113; ZUFSP; Zinc finger-containing ubiquitin peptidase 1; EC 3.4.19.12; Lys-63-specific deubiquitinase ZUFSP; DUB; Zinc finger with UFM1-specific peptidase domain protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-578 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96AP4 |
|---|
Uniprot Id
Q96AP4
Target Species
Human
Target Name
ZUP1
Target Full Name
Zinc finger-containing ubiquitin peptidase 1
Target Function
Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains. Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains. Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage. Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Synonyms
ZUP1; C6orf113; ZUFSP; Zinc finger-containing ubiquitin peptidase 1; EC 3.4.19.12; Lys-63-specific deubiquitinase ZUFSP; DUB; Zinc finger with UFM1-specific peptidase domain protein
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