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The antibody against FSTL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_009016.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against FSTL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_009016.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-11363A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FSTL1 |
| Target Synonyms | FRP; FSL1; OCC1; OCC-1; tsc36; MIR198; FSTL1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat heart, Mouse brain, OVCAR3 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_009016.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q12841 | Immunogen Sequence |
Uniprot Id
Q12841
Target Species
Human
Target Name
FSTL1
Target Full Name
Follistatin-related protein 1
Target Function
Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Overexpressed in synovial tissues from rheumatoid arthritis.
Target Synonyms
Anti FSTL1; FLJ50214; FLJ52277; Follistatin like 1; Follistatin related protein ; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1; FSTL1_HUMAN; Micro RNA 198; MIR198; miRNA198 included; OCC 1; OCC1
Target Background
This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis.
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