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Rabbit anti-Human SOX1 Monoclonal Antibody

The antibody against SOX1 was raised in Rabbit using the recombinant protein of human SOX1 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-15280A

The antibody against SOX1 was raised in Rabbit using the recombinant protein of human SOX1 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-15280A ClonalityMonoclonal
Host SpeciesRabbitTarget NameSOX1
Target SynonymsSOX1; SRY-box 1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesC6, Mouse brain, Neuro-2aApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant protein of human SOX1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO00570
Background Information
  • Uniprot Id

    O00570

  • Target Species

    Human

  • Target Name

    SOX1

  • Target Full Name

    Transcription factor SOX-1

  • Target Function

    Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Mainly expressed in the developing central nervous system.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    Sex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1

  • Target Background

    This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.

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