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| Cat.No | ACP00238 | Target Name | CHIC2 |
|---|---|---|---|
| Target Synonyms | BrX-like translocated in leukemia | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-165aa |
| Mol Weight | 27.0 kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UKJ5 |
|---|
Uniprot Id
Q9UKJ5
Target Species
Human
Target Name
CHIC2
Target Full Name
Cysteine-rich hydrophobic domain-containing protein 2
Target Involvement
A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6.
Target Subcellular Location
Cell membrane. Cytoplasmic vesicle. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles.
Target Protein Families
CHIC family
Target Research Area
Others
Target Synonyms
BrX-like translocated in leukemia; BTL; Chic2; CHIC2_HUMAN; Cystein-rich hydrophobic domain 2; Cysteine-rich hydrophobic domain 2 protein; MGC21173
Target Background
This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia.
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