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Recombinant Human RNA-binding protein PNO1 (PNO1)

ACP00583

Number
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Specifications


Cat.No ACP00583 Target NamePNO1
Target SynonymsPartner of NOB1FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range1-252aa
Mol Weight34.8 kDaProtein LengthFull length
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NRX1
Background Information
  • Uniprot Id

    Q9NRX1

  • Target Species

    Human

  • Target Name

    PNO1

  • Target Full Name

    RNA-binding protein PNO1

  • Target Function

    Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.

  • Target Subcellular Location

    Nucleus, nucleolus.

  • Target Protein Families

    PNO1 family

  • Target Tissue Specificity

    Expressed in liver, lung, spleen and kidney. Weakly expressed in thymus, testis and ovary. Weakly or not expressed in heart, brain, skeletal muscle, placenta, pancreas, prostate, small intestine, colon and peripheral blood leukocytes.

  • Target Research Area

    Cancer

  • Target Synonyms

    PNO1; RNA-binding protein PNO1

  • Target Background

    Enables RNA binding activity. Located in nucleolus and nucleoplasm.

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