Recombinant Human Osteopontin (SPP1)

Cat.No	ACP02106	Target Name	SPP1
Form	Liquid or Lyophilized powder	Expression System	Yeast
Expression Range	17-300aa	Mol Weight	34.2 kDa
Protein Length	Full Length of Mature Protein of Isoform 5	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP02106

Target Name

SPP1

Form

Liquid or Lyophilized powder

Expression System

Yeast

Expression Range

17-300aa

Mol Weight

34.2 kDa

Protein Length

Full Length of Mature Protein of Isoform 5

Purity

Greater than 90% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P10451

Background Information

Uniprot Id

P10451
Target Species

Human
Target Name

SPP1
Target Full Name

Osteopontin
Target Function

Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.; Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
Target Subcellular Location

Secreted.
Target Protein Families

Osteopontin family
Target Tissue Specificity

Bone. Found in plasma.
Target Research Area

Cancer
Target Synonyms

BNSP; Bone sialoprotein 1; Bone sialoprotein I; BSP I; BSPI; Early T lymphocyte activation 1; ETA 1; ETA1; MGC110940; Nephropontin; OPN; Osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; OSTP_HUMAN; PSEC0156; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1; SPP 1; SPP-1; SPP1; SPP1/CALPHA1 fusion; Urinary stone protein; Uropontin
Target Background

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

Recombinant Human Osteopontin (SPP1)

Specifications

Immunogen Information

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