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Recombinant Human Nuclear nucleic acid-binding protein C1D (C1D), Truncated

ACP02995

Number
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Specifications


Cat.No ACP02995 Target NameC1D
FormLiquid or Lyophilized powderExpression SystemE.coli
Expression Range1-135aaMol Weight42.4kDa
Protein LengthPartialPurityGreater than 90% as determined by SDS-PAGE.
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ13901
Background Information
  • Uniprot Id

    Q13901

  • Target Species

    Human

  • Target Name

    C1D

  • Target Full Name

    Nuclear nucleic acid-binding protein C1D

  • Target Function

    Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.

  • Target Subcellular Location

    Nucleus. Cytoplasm. Nucleus, nucleolus.

  • Target Protein Families

    C1D family

  • Target Tissue Specificity

    Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung an

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    1110036E10Rik; AI875855; C1D; C1D DNA binding protein; C1D_HUMAN; hC1D; LRP1; MGC12261; MGC14659; MGC188504; Nuclear DNA binding protein; Nuclear nucleic acid binding protein C1D; Nuclear nucleic acid-binding protein C1D; rCG23324; RGD1560600; Small unique nuclear receptor corepressor; SUNCOR

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