Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
Discover our premium-quality Recombinant Human Proepiregulin (EREG) protein, a valuable tool for researchers focusing on cancer-related studies. Proepiregulin, also known as Epiregulin or EPR, is a member of the epidermal growth factor (EGF) family, playing a significant role in cell growth, proliferation, and differentiation, thereby contributing to cancer progression and metastasis. Our Recombinant Human Proepiregulin (EREG) protein is expressed in an E.coli system and contains the extracellular domain (60-119aa) for optimal research applications. The N-terminal 6xHis-SUMO tag ensures efficient purification and detection processes. With a purity of greater than 90% as determined by SDS-PAGE, this protein offers reliable performance for your cancer research. Available in both liquid and lyophilized powder forms, our Recombinant Human Proepiregulin (EREG) protein is designed to suit the diverse needs of your scientific endeavors.
Discover our premium-quality Recombinant Human Proepiregulin (EREG) protein, a valuable tool for researchers focusing on cancer-related studies. Proepiregulin, also known as Epiregulin or EPR, is a member of the epidermal growth factor (EGF) family, playing a significant role in cell growth, proliferation, and differentiation, thereby contributing to cancer progression and metastasis.
Our Recombinant Human Proepiregulin (EREG) protein is expressed in an E.coli system and contains the extracellular domain (60-119aa) for optimal research applications. The N-terminal 6xHis-SUMO tag ensures efficient purification and detection processes. With a purity of greater than 90% as determined by SDS-PAGE, this protein offers reliable performance for your cancer research. Available in both liquid and lyophilized powder forms, our Recombinant Human Proepiregulin (EREG) protein is designed to suit the diverse needs of your scientific endeavors.
| Cat.No | ACP03775 | Target Name | EREG |
|---|---|---|---|
| Target Synonyms | Epiregulin; EPR; ER ; Ereg; EREG_HUMAN; Proepiregulin | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 60-119aa |
| Mol Weight | 22.9kDa | Protein Length | Extracellular Domain |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14944 |
|---|
Uniprot Id
O14944
Target Species
Human
Target Name
EREG
Target Full Name
Proepiregulin
Target Function
Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation. Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation.
Target Subcellular Location
[Epiregulin]: Secreted, extracellular space.; [Proepiregulin]: Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.
Target Research Area
Cancer
Target Synonyms
Epiregulin; EPR; ER ; Ereg; EREG_HUMAN; Proepiregulin
Target Background
This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
