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Recombinant Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15), Truncated

This Recombinant Human SIGLEC15 protein is a powerful resource for researchers investigating sialic acid-binding Ig-like lectin 15 (Siglec-15). Known for its roles in various biological processes, including immune regulation and cell adhesion, SIGLEC15 is a valuable target for scientific exploration in both health and disease. Our Recombinant Human SIGLEC15 protein is expressed in E.coli, resulting in the production of the extracellular domain (20-263aa). This protein features an N-terminal 6xHis-SUMO tag, allowing for efficient purification and detection while maintaining native structure and function. With a purity greater than 90% as determined by SDS-PAGE, this Recombinant Human SIGLEC15 protein delivers the reliability and consistency essential for your research efforts. Choose between liquid and lyophilized powder formats to best accommodate your experimental requirements.

ACP03798

This Recombinant Human SIGLEC15 protein is a powerful resource for researchers investigating sialic acid-binding Ig-like lectin 15 (Siglec-15). Known for its roles in various biological processes, including immune regulation and cell adhesion, SIGLEC15 is a valuable target for scientific exploration in both health and disease.
Our Recombinant Human SIGLEC15 protein is expressed in E.coli, resulting in the production of the extracellular domain (20-263aa). This protein features an N-terminal 6xHis-SUMO tag, allowing for efficient purification and detection while maintaining native structure and function. With a purity greater than 90% as determined by SDS-PAGE, this Recombinant Human SIGLEC15 protein delivers the reliability and consistency essential for your research efforts. Choose between liquid and lyophilized powder formats to best accommodate your experimental requirements.

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Specifications


Cat.No ACP03798 Target NameSIGLEC15
Target SynonymsCD33 antigen-like 3; CD33 molecule-like 3; CD33L3; HsT1361; Sialic acid-binding Ig-like lectin 15; SIG15_HUMAN; Siglec-15; SIGLEC15FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range20-263aa
Mol Weight42.6kDaProtein LengthExtracellular Domain
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6ZMC9
Background Information
  • Uniprot Id

    Q6ZMC9

  • Target Species

    Human

  • Target Name

    SIGLEC15

  • Target Full Name

    Sialic acid-binding Ig-like lectin 15

  • Target Function

    Binds sialylated glycoproteins.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family

  • Target Tissue Specificity

    Expressed in macrophage and/or dendritic cells of spleen and lymph nodes.

  • Target Research Area

    Others

  • Target Synonyms

    CD33 antigen-like 3; CD33 molecule-like 3; CD33L3; HsT1361; Sialic acid-binding Ig-like lectin 15; SIG15_HUMAN; Siglec-15; SIGLEC15

  • Target Background

    Predicted to be involved in regulation of actin cytoskeleton organization; regulation of bone resorption; and regulation of osteoclast development. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane.

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