Recombinant Human Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)

Recombinant Human HNRNPA2B1 protein (HNRNPA2B1) is a full length protein expressed with an N-terminal 6xHis-tagged in the yeast. Its expression region corresponds to 1-249aa of human HNRNPA2B1 protein. Its purity was determined by SDS-PAGE and reached up to 90% and presented a molecular mass band around 30 kDa on the gel. This recombinant HNRNPA2B1 protein may be used to synthesize antibodies against HNRNPA2B1 or on the studies of HNRNPA2B1-associated signal transduction. The HNRNPA2B1 gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs proteins are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). All of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties and two repeats of quasi-RRM domains that bind to RNAs.