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Recombinant Human Translation initiation factor IF-3, mitochondrial (MTIF3)

ACP04876

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP04876 Target NameMTIF3
Target SynonymsDC38; IF 3 ; IF 3Mt; IF-3(Mt); IF-3Mt; IF3 ; IF3(mt); IF3M_HUMAN; IF3mt; mitochondrial; Mt; MTIF3; Translation initiation factor IF 3; mitochondrial precursor; Translation initiation factor IF-3FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range1-278aa
Mol Weight55.2kDaProtein LengthFull length
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9H2K0
Background Information
  • Uniprot Id

    Q9H2K0

  • Target Species

    Human

  • Target Name

    MTIF3

  • Target Full Name

    Translation initiation factor IF-3, mitochondrial

  • Target Function

    IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    IF-3 family

  • Target Research Area

    Neuroscience

  • Target Synonyms

    DC38; IF 3 ; IF 3Mt; IF-3(Mt); IF-3Mt; IF3 ; IF3(mt); IF3M_HUMAN; IF3mt; mitochondrial; Mt; MTIF3; Translation initiation factor IF 3; mitochondrial precursor; Translation initiation factor IF-3

  • Target Background

    This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

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