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Recombinant Human Transient receptor potential cation channel subfamily M member 6 (TRPM6), Truncated

ACP05798

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Specifications

Cat.No	ACP05798	Target Name	TRPM6
Target Synonyms	TRPM6; CHAK2Transient receptor potential cation channel subfamily M member 6; EC 2.7.11.1; Channel kinase 2; Melastatin-related TRP cation channel 6	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BX84

Background Information

Uniprot Id

Q9BX84
Target Species

Human
Target Name

TRPM6
Target Full Name

Transient receptor potential cation channel subfamily M member 6
Target Function

Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region.
Target Involvement

Hypomagnesemia 1 (HOMG1)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily; Transient receptor (TC 1.A.4) family, LTrpC subfamily, TRPM6 sub-subfamily
Target Tissue Specificity

Highly expressed in kidney and colon. Isoform TRPM6a and isoform TRPM6b, are coexpressed with TRPM7 in kidney, and testis, and are also found in several cell lines of lung origin. Isoform TRPM6c is detected only in testis and in NCI-H510A small cell lung
Target Synonyms

TRPM6; CHAK2Transient receptor potential cation channel subfamily M member 6; EC 2.7.11.1; Channel kinase 2; Melastatin-related TRP cation channel 6

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Recombinant Human Transient receptor potential cation channel subfamily M member 6 (TRPM6), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Transient receptor potential cation channel subfamily M member 6 (TRPM6), Truncated Now

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