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| Cat.No | ACP05897 | Target Name | COQ2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96H96 |
|---|
Uniprot Id
Q96H96
Target Species
Human
Target Name
COQ2
Target Full Name
4-hydroxybenzoate polyprenyltransferase, mitochondrial
Target Function
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
Target Involvement
Coenzyme Q10 deficiency, primary, 1 (COQ10D1); Multiple system atrophy 1 (MSA1)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Target Protein Families
UbiA prenyltransferase family
Target Tissue Specificity
Widely expressed. Present in all of the tissues tested. Expressed at higher level in skeletal muscle, adrenal glands and the heart.
Target Synonyms
2310002F18Rik; 4-hydroxybenzoate polyprenyltransferase; CL640; Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase; Coenzyme Q2 homolog; prenyltransferase (yeast); COQ10D1; COQ2; COQ2 homolog; COQ2_HUMAN; FLJ13014; FLJ26072; hCOQ2; MGC124824; MGC91278; mitochondrial; MSA1; OTTMUSP00000032111; Para-hydroxybenzoate--polyprenyltransferase; Para-hydroxybenzoate--polyprenyltransferase; mitochondrial; PHB:polyprenyltransferase; RGD1306722
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