Recombinant Human V-type proton ATPase 116 kDa subunit a isoform 3 (TCIRG1), Truncated

Cat.No	ACP06209	Target Name	TCIRG1
Target Synonyms	ATPase, H+ transporting, immune regulator 1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP06209

Target Name

TCIRG1

Target Synonyms

ATPase, H+ transporting, immune regulator 1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q13488

Background Information

Uniprot Id

Q13488
Target Species

Human
Target Name

TCIRG1
Target Full Name

V-type proton ATPase 116 kDa subunit a 3
Target Function

Part of the proton channel of V-ATPases. Seems to be directly involved in T-cell activation.
Target Involvement

Osteopetrosis, autosomal recessive 1 (OPTB1)
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

V-ATPase 116 kDa subunit family
Target Tissue Specificity

Isoform long is highly expressed in osteoclastomas. Isoform short is highly expressed in thymus.
Target Synonyms

a3; Atp 6i; Atp6i; ATP6N1C; ATP6V0A3; ATPase H+ transporting 116kD; OC 116; OC 116 kDa; OC 116kDa; OC-116 kDa; OC116; OPTB 1; OPTB1; Osteoclastic proton pump 116 kDa subunit; Specific 116 kDa vacuolar proton pump subunit; Stv 1; Stv1; T cell immune regulator 1; T cell immune regulator 1 ATPase H+ transporting lysosomal V0 subunit A; T cell immune regulator 1 ATPase H+ transporting lysosomal V0 subunit A3; T cell immune response cDNA 7; T cell immune response cDNA7 protein; T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a; T-cell immune regulator 1; T-cell immune response cDNA7 protein; TCIRG 1; TCIRG1; TIRC 7; TIRC7; V ATPase 116 kDa; V ATPase 116 kDa isoform a3; V type proton ATPase 116 kDa subunit a; V-ATPase 116 kDa isoform a3; V-type proton ATPase 116 kDa subunit a isoform 3; Vacuolar proton translocating ATPase 116 kDa subunit A; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3; Vph 1; Vph1; VPP3_HUMAN
Target Background

This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.

Recombinant Human V-type proton ATPase 116 kDa subunit a isoform 3 (TCIRG1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human V-type proton ATPase 116 kDa subunit a isoform 3 (TCIRG1), Truncated Now

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