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| Cat.No | ACP08495 | Target Name | TM7SF3 |
|---|---|---|---|
| Target Synonyms | TM7SF3; Transmembrane 7 superfamily member 3; Seven span transmembrane protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NS93 |
|---|
Uniprot Id
Q9NS93
Target Species
Human
Target Name
TM7SF3
Target Full Name
Transmembrane 7 superfamily member 3
Target Function
Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells. Is a downstream transcriptional target of p53/TP53, and acts as a pro-survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR).
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Tissue Specificity
Widely expressed. Highly expressed in kidney and pancreas.
Target Synonyms
TM7SF3; Transmembrane 7 superfamily member 3; Seven span transmembrane protein
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