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| Cat.No | ACP09426 | Target Name | HS3ST3B1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y662 |
|---|
Uniprot Id
Q9Y662
Target Species
Human
Target Name
HS3ST3B1
Target Full Name
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1
Target Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Sulfotransferase 1 family
Target Tissue Specificity
Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney.
Target Synonyms
HS3ST3B1; 3OST3B1; HS3ST3BHeparan sulfate glucosamine 3-O-sulfotransferase 3B1; EC 2.8.2.30; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; 3-OST-3B; Heparan sulfate 3-O-sulfotransferase 3B1; h3-OST-3B
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