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Recombinant Human Heat shock protein beta-7 (HSPB7)

ACP10187

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10187 Target NameHSPB7
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-170Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UBY9
Background Information
  • Uniprot Id

    Q9UBY9

  • Target Species

    Human

  • Target Name

    HSPB7

  • Target Full Name

    Heat shock protein beta-7

  • Target Subcellular Location

    Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

  • Target Protein Families

    Small heat shock protein (HSP20) family

  • Target Tissue Specificity

    Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.

  • Target Synonyms

    Cardiovascular heat shock protein; cvHsp; DKFZp779D0968; FLJ32733; Heat shock 27kda protein family member 7; Heat shock protein beta 7; Heat shock protein beta-7; Hsp25 2; HspB7; HSPB7_HUMAN; Hypothetical protein flj34956; RP11-5P18.6

  • Target Background

    This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma.

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