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| Cat.No | ACP10379 | Target Name | NACA2 |
|---|---|---|---|
| Target Synonyms | NACA2; NACAL; Nascent polypeptide-associated complex subunit alpha-2; Alpha-NAC-like; Hom s 2.01; Nascent polypeptide-associated complex subunit alpha-like; NAC-alpha-like | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-215 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H009 |
|---|
Uniprot Id
Q9H009
Target Species
Human
Target Name
NACA2
Target Full Name
Nascent polypeptide-associated complex subunit alpha-2
Target Function
Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
NAC-alpha family
Target Tissue Specificity
Expressed specifically in testis and skeletal muscle.
Target Synonyms
NACA2; NACAL; Nascent polypeptide-associated complex subunit alpha-2; Alpha-NAC-like; Hom s 2.01; Nascent polypeptide-associated complex subunit alpha-like; NAC-alpha-like
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