Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (HMG20B)

Uniprot Id

Q9P0W2

Target Species

Human

Target Name

HMG20B

Target Full Name

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

Target Function

Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.

Target Subcellular Location

Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2.

Target Tissue Specificity

Ubiquitously expressed in adult tissues.

Target Synonyms

BRAF25; BRAF35; BRCA2 associated factor 35; BRCA2-associated factor 35; High Mobility Group Protein 20B; HM20B_HUMAN; HMG box containing protein 20B; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; HMG20B; SMARCE1-related protein; SMARCE1r; sox like; Sox like transcriptional factor; Sox-like transcriptional factor; SOXL; Structural DNA binding protein BRAF35; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

Target Background

Predicted to enable DNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of protein sumoylation; positive regulation of neuron differentiation; and skeletal muscle cell differentiation. Located in nuclear body.