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Recombinant Human DnaJ homolog subfamily C member 27 (DNAJC27)

ACP11973

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11973 Target NameDNAJC27
Target SynonymsDJC27_HUMAN; DKFZp434N211; DnaJ (Hsp40) homolog, member 27; DnaJ homolog subfamily C member 27; DNAJC27; rab and DnaJ domain containing; Rab and DnaJ domain-containing protein; RABJS; Ras associated protein Rap1; RBJ, subfamily CFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-273
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NZQ0
Background Information
  • Uniprot Id

    Q9NZQ0

  • Target Species

    Human

  • Target Name

    DNAJC27

  • Target Full Name

    DnaJ homolog subfamily C member 27

  • Target Function

    GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Small GTPase superfamily, Rab family

  • Target Tissue Specificity

    Overexpressed in gastrointestinal cancers; expression correlates with later tumor-node-metastasis stages of colorectal cancers.

  • Target Synonyms

    DJC27_HUMAN; DKFZp434N211; DnaJ (Hsp40) homolog, subfamily C, member 27; DnaJ homolog subfamily C member 27; DNAJC27; rab and DnaJ domain containing; Rab and DnaJ domain-containing protein; RABJS; Ras associated protein Rap1; RBJ

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