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| Cat.No | ACP14254 | Target Name | EHBP1 |
|---|---|---|---|
| Target Synonyms | EHBP1; KIAA0903; NACSINEH domain-binding protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NDI1 |
|---|
Uniprot Id
Q8NDI1
Target Species
Human
Target Name
EHBP1
Target Full Name
EH domain-binding protein 1
Target Function
May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking. Required for perinuclear sorting and insulin-regulated recycling of SLC2A4/GLUT4 in adipocytes.
Target Involvement
Prostate cancer, hereditary, 12 (HPC12)
Target Subcellular Location
Cytoplasm. Membrane. Endosome. Note=Mostly found in cytosol and plasma membrane.
Target Synonyms
EHBP1; KIAA0903; NACSINEH domain-binding protein 1
Target Background
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants.
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