Recombinant Human C-type lectin domain family 2 member B (CLEC2B), Truncated

Uniprot Id

Q92478

Target Species

Human

Target Name

CLEC2B

Target Full Name

C-type lectin domain family 2 member B

Target Subcellular Location

Membrane; Single-pass type II membrane protein.

Target Tissue Specificity

Expressed preferentially in lymphoid tissues, and in most hematopoietic cell types.

Target Synonyms

CLEC2B; AICL; CLECSF2; IFNRG1C-type lectin domain family 2 member B; Activation-induced C-type lectin; C-type lectin superfamily member 2; IFN-alpha-2b-inducing-related protein 1

Target Background

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.