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| Cat.No | ACP15019 | Target Name | FMNL3 |
|---|---|---|---|
| Target Synonyms | FMNL3; FHOD3; FRL2; KIAA2014; WBP3; Formin-like protein 3; Formin homology 2 domain-containing protein 3; WW domain-binding protein 3; WBP-3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IVF7 |
|---|
Uniprot Id
Q8IVF7
Target Species
Human
Target Name
FMNL3
Target Full Name
Formin-like protein 3
Target Function
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis. In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignement.
Target Subcellular Location
Cytoplasm. Cell membrane; Lipid-anchor. Note=Enriched in lamellipodia.
Target Protein Families
Formin homology family
Target Tissue Specificity
Expressed in endothelial cells.
Target Synonyms
FMNL3; FHOD3; FRL2; KIAA2014; WBP3; Formin-like protein 3; Formin homology 2 domain-containing protein 3; WW domain-binding protein 3; WBP-3
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