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Recombinant Human A-kinase anchor protein 14 (AKAP14)

ACP15691

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15691 Target NameAKAP14
Target SynonymsAKAP14; AKAP28A-kinase anchor protein 14; AKAP-14; A-kinase anchor protein 28 kDa; AKAP 28; Protein kinase A-anchoring protein 14; PRKA14FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-197
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ86UN6
Background Information
  • Uniprot Id

    Q86UN6

  • Target Species

    Human

  • Target Name

    AKAP14

  • Target Full Name

    A-kinase anchor protein 14

  • Target Function

    Binds to type II regulatory subunits of protein kinase A and anchors/targets them.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Present in cilia (at protein level). Expressed in tissues containing axoneme-based organelles (cilia and/or flagella): trachea and testis. Highly expressed in airway cilia.

  • Target Synonyms

    AKAP14; AKAP28A-kinase anchor protein 14; AKAP-14; A-kinase anchor protein 28 kDa; AKAP 28; Protein kinase A-anchoring protein 14; PRKA14

  • Target Background

    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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