Recombinant Human Kazrin (KAZN)

Cat.No	ACP16732	Target Name	KAZN
Target Synonyms	HRIHFB2003; KAZ; Kazn; Kazrin; KAZRN_HUMAN; KIAA1026; RP1-21O18.1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-775
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP16732

Target Name

KAZN

Target Synonyms

HRIHFB2003; KAZ; Kazn; Kazrin; KAZRN_HUMAN; KIAA1026; RP1-21O18.1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-775

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q674X7

Background Information

Uniprot Id

Q674X7
Target Species

Human
Target Name

KAZN
Target Full Name

Kazrin
Target Function

Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
Target Subcellular Location

Cytoplasm, cytoskeleton.; [Isoform 2]: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 3]: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.; [Isoform 4]: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.
Target Protein Families

Kazrin family
Target Tissue Specificity

Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at pro
Target Synonyms

HRIHFB2003; KAZ; Kazn; Kazrin; KAZRN_HUMAN; KIAA1026; RP1-21O18.1

Recombinant Human Kazrin (KAZN)

Specifications

Immunogen Information

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