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| Cat.No | ACP16799 | Target Name | RRAGB |
|---|---|---|---|
| Target Synonyms | RRAGB; Ras-related GTP-binding protein B; Rag B; RagB | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-374 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5VZM2 |
|---|
Uniprot Id
Q5VZM2
Target Species
Human
Target Name
RRAGB
Target Full Name
Ras-related GTP-binding protein B
Target Function
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
Target Subcellular Location
Cytoplasm. Lysosome.
Target Protein Families
GTR/RAG GTP-binding protein family
Target Synonyms
RRAGB; Ras-related GTP-binding protein B; Rag B; RagB
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