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| Cat.No | ACP16866 | Target Name | METTL11B |
|---|---|---|---|
| Target Synonyms | METTL11B; C1orf184; NRMT2; Alpha N-terminal protein methyltransferase 1B; EC 2.1.1.299; Methyltransferase-like protein 11B; X-Pro-Lys N-terminal protein methyltransferase 1B; NTM1B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-283 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5VVY1 |
|---|
Uniprot Id
Q5VVY1
Target Species
Human
Target Name
NTMT2
Target Full Name
N-terminal Xaa-Pro-Lys N-methyltransferase 2
Target Function
Alpha N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes monomethylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and Pro in the Pro-Pro-Lys motif. Predominantly functions as a mono-methyltransferase but is also able to di-/tri-methylate the GPKRIA peptide and di-methylate the PPKRIA peptide (in vitro). May activate NTMT1 by priming its substrates for trimethylation.
Target Subcellular Location
Nucleus.
Target Protein Families
Methyltransferase superfamily, NTM1 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
METTL11B; C1orf184; NRMT2; Alpha N-terminal protein methyltransferase 1B; EC 2.1.1.299; Methyltransferase-like protein 11B; X-Pro-Lys N-terminal protein methyltransferase 1B; NTM1B
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