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| Cat.No | ACP17162 | Target Name | ESCO1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5FWF5 |
|---|
Uniprot Id
Q5FWF5
Target Species
Human
Target Name
ESCO1
Target Full Name
N-acetyltransferase ESCO1
Target Function
Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Acetyltransferase family, ECO subfamily
Target Tissue Specificity
Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle.
Target Synonyms
A930014I12Rik; CTF; CTF7 homolog 1; CTF7; S. cerevisiae; homolog of; 1; ECO1; ECO1 homolog 1; ECO1; S. cerevisiae; homolog of; 1; EFO1; EFO1p; ESCO1; ESCO1_HUMAN; ESO1; ESO1 homolog 1; ESO1; S. pombe; homolog of; 1; Establishment factor like protein 1; Establishment factor ortholog 1; Establishment factor-like protein 1; Establishment of cohesion 1 homolog 1; Establishment of cohesion 1; S. cerevisiae; homolog of; establishment of sister chromatid cohesion N-acetyltransferase 1; hEFO1; HGNC:24645; KIAA1911; N acetyltransferase ESCO1; N-acetyltransferase ESCO1
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