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Recombinant Human Ras-specific guanine nucleotide-releasing factor RalGPS1 (RALGPS1)

ACP17365

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17365 Target NameRALGPS1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-557Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5JS13
Background Information
  • Uniprot Id

    Q5JS13

  • Target Species

    Human

  • Target Name

    RALGPS1

  • Target Full Name

    Ras-specific guanine nucleotide-releasing factor RalGPS1

  • Target Function

    Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization. Guanine nucleotide exchange factor for.

  • Target Subcellular Location

    Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain.

  • Target Tissue Specificity

    Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, p

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    RALGPS1; KIAA0351; RALGEF2; Ras-specific guanine nucleotide-releasing factor RalGPS1; Ral GEF with PH domain and SH3-binding motif 1; Ral guanine nucleotide exchange factor 2; RalGEF 2; RalA exchange factor RalGPS1

  • Target Background

    Enables guanyl-nucleotide exchange factor activity. Involved in regulation of Ral protein signal transduction. Predicted to be located in cytoplasm and plasma membrane.

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