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| Cat.No | ACP17595 | Target Name | SMU1 |
|---|---|---|---|
| Target Synonyms | SMU1; WD40 repeat-containing protein SMU1; Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1; N-terminally processed] | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-513 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q2TAY7 |
|---|
Uniprot Id
Q2TAY7
Target Species
Human
Target Name
SMU1
Target Full Name
WD40 repeat-containing protein SMU1
Target Function
Involved in pre-mRNA splicing as a component of the spliceosome. Regulates alternative splicing of the HSPG2 pre-mRNA. Required for normal accumulation of IK. Required for normal mitotic spindle assembly and normal progress through mitosis.; (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Target Subcellular Location
Cytoplasm. Nucleus. Nucleus speckle.
Target Protein Families
WD repeat SMU1 family
Target Synonyms
SMU1; WD40 repeat-containing protein SMU1; Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1; N-terminally processed]
Target Background
Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome.
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