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| Cat.No | ACP17635 | Target Name | SPRED3 |
|---|---|---|---|
| Target Synonyms | SPRED3; EVE-3; Sprouty-related; EVH1 domain-containing protein 3; Spred-3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-410 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q2MJR0 |
|---|
Uniprot Id
Q2MJR0
Target Species
Human
Target Name
SPRED3
Target Full Name
Sprouty-related, EVH1 domain-containing protein 3
Target Function
Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Target Subcellular Location
Cell membrane; Peripheral membrane protein.
Target Synonyms
SPRED3; EVE-3; Sprouty-related; EVH1 domain-containing protein 3; Spred-3
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